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Interactions

Stranglefield S, et al. 2019. Tadalafil vs sildenafil for erectile dysfunction: A multicenter, randomized, double-blind study. Sexual Medicine. Accessed July 14, 2019.

About interactions

Cialis (tadalafil) is a medication that belongs to a class of drugs called phosphodiesterase type 5 inhibitors. It is most commonly used to treat erectile dysfunction, but may also be used off-label for other conditions such as pulmonary arterial hypertension and benign prostatic hyperplasia. In addition, tadalafil also treats benign prostatic hyperplasia (BPH) by relaxing the muscles in the bladder and prostate. This makes it effective for both acute and chronic BPH.

Cialis may cause side effects such as headache, flushing, nasal congestion, and back pain. These side effects are usually mild and temporary. However, if you experience any of these symptoms while taking Cialis, seek medical advice from your healthcare provider.

Risks

Cialis may increase the risk of developing a condition called benign prostatic hyperplasia. If you are taking tadalafil and have BPH, you may be at higher risk for this condition. If you develop these symptoms while taking Cialis, talk to your healthcare provider about adjusting the dosage or switching to tadalafil.

The use of Cialis for pulmonary arterial hypertension (PAH) increases the risk of severe adverse effects, such as sudden vision loss, hearing loss, or chest pain. If you are taking tadalafil or nitrates for angina or other heart conditions, talk to your healthcare provider before taking Cialis.

In rare cases, Cialis may cause low blood pressure. If you are taking nitrates for chest pain, you should inform your healthcare provider of all the risks you have been involved in. Your healthcare provider will monitor your blood pressure after taking Cialis and may adjust the dosage or prescribe a lower dose if necessary.

Dosage

The dosage of Cialis varies depending on the condition being treated. Cialis comes in 30mg, 50mg, and 100mg formulations. The recommended starting dose of Cialis is 50mg, taken approximately one hour before sexual activity. Depending on the severity of the BPH condition and how the body responds to the medication, your healthcare provider may increase the dosage to 100mg once daily. Cialis is typically taken on an empty stomach.

Discuss any other medication or complementary therapies with your healthcare provider to get the best management plan. Especially tell your healthcare provider if you take any medications, including over-the-counter drugs and supplements, that interact with Cialis.

Pulmonary arterial hypertension (PAH) is a condition that causes narrowing of the arteries that supply blood and make it difficult to get or keep an erection. This condition is most common in men over 40 years of age and affects over two-thirds of the world's population. PAH can be caused by heart disease, diabetes, high cholesterol, certain medications, or tumors such as high-grade pulmonary arterial hypertension (PAH-III).

Usage and dosage

Cialis (tadalafil) should be taken as prescribed by a healthcare provider. The recommended starting dose is one tablet about one hour before sexual activity. Depending on the severity of the BPH condition and how the body responds to the medication, your healthcare provider may increase the dosage to one tablet a day.

Cialis should be taken with a full glass of water. It's important to take the medication exactly as directed by your healthcare provider. Do not take more than one dose within a 24-hour period. If you take more than one dose of Cialis, you may experience a side effect that is worse. For example, you might experience flushing, nasal congestion, and dizziness.

Taking Cialis with other medications can increase the risk of side effects. It's important not to self-treat without consulting your healthcare provider.

Cialis can cause low blood pressure.

In some rare cases, Cialis may cause low blood pressure. If you are taking nitrates for angina or other heart conditions, you should inform your healthcare provider of all the risks you have been involved in.

Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Cialis use include:

  • Headache
  • Indigestion
  • Heartburn
  • Upset stomach
  • Gas
  • Nausea
  • Flushing

More severe side effects include:

  • Painful erections or erections that last longer than 4 hours
  • Sudden loss of vision
  • Sudden loss of hearing
  • Ringing in the ears
  • Chest pain
  • Shortness of breath
  • Painful urination
  • Increased urination frequency
  • Fainting
  • Dizziness
  • Skin rash
  • Hives
  • Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

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As with any prescription medication, Cialis can cause some side effects. Use of Cialis can lead to serious adverse reactions that require immediate medical attention, including:

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As with all prescription medications, Cialis can cause some side effects. Side effects include:

  • Gastrointestinal effects
  • Muscle aches
  • Back pain

These are symptoms of a severe adverse reaction to this medication that requires immediate treatment.

  • Stomach pain
  • Painful erections
  • Whusband’s libido drug
  • Sudden loss of vision in one or both eyes

These are side effects that require immediate treatment, including:

  • Sudden loss of vision in one or both eyes ( blur vision
  • Sudden loss of vision in one or both eyes ( vision loss
  • Flu-like symptoms

Sildenafil citrate, commonly known by the brand name, is a prescription-only medicine used to treat erectile dysfunction (ED) in adult men. It works by improving blood flow to the penis, helping to achieve and maintain an erection during sexual activity.

Dosage and Administration

Sildenafil is available in 25mg, 50mg, and 100mg strengths.

  • The usual starting dose is 50mg, taken approximately one hour before sexual activity.
  • Dosage can be adjusted depending on individual response and tolerability.
  • Take only one tablet in 24 hours, with or without food.
  • Avoid grapefruit juice, as it can increase the risk of side effects.
  • A high-fat meal may delay onset of action.

Effectiveness

Sildenafil has been shown to be effective in up to 80% of men with ED, with effects typically noticeable within 30 to 60 minutes, and lasting for up to 4–5 hours.

Side Effects

Common side effects include:

  • Headache
  • Flushing
  • Nasal congestion
  • Indigestion

Less common but serious effects include visual disturbances, hearing changes, or prolonged erections. Seek medical attention if severe or persistent side effects occur.

Contraindications

Sildenafil should not be used by those:

  • Taking nitrates for chest pain
  • With severe heart or liver conditions
  • Under 18 years of age
  • With certain medication interactions (e.g. alpha-blockers, antifungals, antibiotics)

Interactions

Inform your doctor of all medications and supplements before use. Interactions may occur with:

  • Nitrates
  • Alpha-blockers
  • Some antibiotics and antifungal medicines

Alcohol and Heart Conditions

Avoid excessive alcohol while taking sildenafil, as it can lower blood pressure and increase side effect risk. Use with caution if you have any heart-related conditions.

Availability and Cost

Sildenafil is available by prescription only in the UK.

  • Generic versions are more affordable than branded Viagra.
  • Supplied by licensed UK pharmacies such as Online Chemist.
  • Avoid counterfeit products from unregulated websites.

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Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Cialis use include:

  • Headache
  • Indigestion
  • Heartburn
  • Upset stomach
  • Gas
  • Nausea
  • Flushing

More severe side effects include:

  • Painful erections or erections that last longer than 4 hours
  • Sudden loss of vision
  • Sudden loss of hearing
  • Ringing in the ears
  • Chest pain
  • Shortness of breath
  • Painful urination
  • Increased urination frequency
  • Fainting
  • Dizziness
  • Skin rash
  • Hives
  • Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

asthma are among 1 in 10 people taking Cialis

As with any medication, Cialis can cause potentially serious adverse reactions that need medical attention. These include:

  • Signs of liver problems
  • Confusion
  • Fatigue
  • Dark urine
  • Heart attack or stroke
  • nea or recent heart attack
  • Severe skin reactions (such as exudate or blackops)
  • Priapism

In addition, inform your health care provider of any pelvic organ pain or enlargement and if you are taking other medications for erectile dysfunction. These symptoms are similar to those seen with sexual activity.

As with any medication, Cialis can affect the function of a sexual capacity. If you have a history of heart disease, low blood pressure, diabetes, or a history of heart surgery, inform your health care provider about any prior history of these conditions. These conditions may be taking special care under your doctor’s care.

Dr. Michael Jordan, a renowned cardiovascular health provider, is the leading authority on erectile dysfunction and can be reached at or [1-800-222-1222]. As a doctor, you have an up-to-date health information like medical history, symptoms, and potential drug interactions. If you’re experiencing a side effect, contact your health care provider by calling 9-1-1 immediately [1-800-222-1222].

asthma can result from any medication containing nitrates used for hypertension [2-5-0] or nitrates used for heart conditions [3-5-24] or nitroglycerin [5-9-0] or nitrite [10-12-0]asthma can also occur as a side effect of Cialis [2-5-0] or nitrates used for heart conditions [3-5-24] or nitrite [10-12-0]